NIMS  is recognized by Medical Council of India. It is administered under the supervision of Governing Council, Executive Board, Director and other statutory bodies.

The institute is located in Punjagutta  area at the prime center of the twin cities and spread over an area of about 23 acres . It has the constructed area of more than six lakh sq.ft. The Institute serves through 27 Departments. Out of them, 14 are Super Specialties and others are Supporting Departments. The Institute has a bed strength of 946, out of which 603 are in General Wards, 166 in private rooms and 177 in emergency and post operative care.

It publishes the monthly journal "The Clinical Proceedings of Nizam's Institute of Medical Sciences" for the last 20 years.

The Nizam's Charitable Trust in 1961 thought of starting a specialty Hospital for orthopaedic patients with an initial investment of Rs. 55 Lakhs. The foundation stone was laid on 16 July 1961 by Sri Morarji Desai, Minister for Finance, Government of India.

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